TNKS-2-IN-1
Product Specifications
CAS Number
4765-59-7
Target
PARP|||Wnt/beta-catenin|||Antibiotic
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Cytoskeletal Signaling|||Microbiology/Virology|||Stem Cells
Purity
0.984
Bioactivity
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the release of IL-1? from the NLRP3 inflammasome (IC50: 5 ?M) by inhibiting IL-1? release from ATP-stimulated J1A.774 cells.
Smiles
[O-][N+](=O)c1ccc(cc1)-c1nc(=O)c2ccccc2[nH]1
Molecular Formula
C14H9N3O3
Molecular Weight
267.24
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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