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KH16

Product Specifications

Target

Apoptosis|||HDAC

Related Pathways

Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Apoptosis

Purity

0.9911

Bioactivity

KH16 is a potent HDAC inhibitor that specifically targets class I HDACs (HDAC1, HDAC2 and HDAC3) with IC50 values between 6 and 34 nM. KH16 is able to stimulate apoptosis and can inhibit gene expression patterns in a wide range of tumor cells.

Smiles

O=C(NO)C(C=N1)=CN=C1N(CC2)CCN2CC3=CNC4=CC=CC=C43

Molecular Formula

C18H20N6O2

Molecular Weight

352.39

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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