Tubulin polymerization-IN-47
Product Specifications
CAS Number
2834087-62-4
Target
Microtubule Associated
Related Pathways
Cytoskeletal Signaling
Purity
0.9969
Bioactivity
Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 and Kelly cell lines, respectively. Tubulin polymerization-IN-47 is a candidate compound for the treatment of hepatocellular carcinoma, colon cancer, lung cancer and breast cancer.
Smiles
O(C)C=1C=C(C=2C=3N(C=C(N3)C4=CC=C(C)C=C4)C=CN2)C=C(OC)C1OC
Molecular Formula
C22H21N3O3
Molecular Weight
375.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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