Multi-kinase-IN-5
Product Specifications
Target
Others, c-Kit, PDGFR, FGFR, VEGFR, c-RET, c-Met/HGFR, Raf
Related Pathways
MAPK, Tyrosine Kinase/Adaptors, Others, Angiogenesis, Apoptosis
Bioactivity
Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that demonstrates significant inhibition of a range of protein kinases, including RET (69%), KIT (31%), cMet (62%), VEGFR1 (40%), VEGFR2 (73%), FGFR1 (74%), PDGFR (59%), and BRAF (74%) . Its IC50 values are 1.287 μM for FGFR1, 0.117 μM for VEGFR, and 1.185 μM for RET kinases, indicating its potency [1].
Molecular Formula
C19H15N5O2S
Molecular Weight
377.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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