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Multi-kinase-IN-5

Product Specifications

Target

Others|||c-Kit|||PDGFR|||FGFR|||VEGFR|||c-RET|||c-Met/HGFR|||Raf

Related Pathways

MAPK|||Tyrosine Kinase/Adaptors|||Others|||Angiogenesis|||Apoptosis

Bioactivity

Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that demonstrates significant inhibition of a range of protein kinases, including RET (69%), KIT (31%), cMet (62%), VEGFR1 (40%), VEGFR2 (73%), FGFR1 (74%), PDGFR (59%), and BRAF (74%) . Its IC50 values are 1.287 ?M for FGFR1, 0.117 ?M for VEGFR, and 1.185 ?M for RET kinases, indicating its potency [1].

Molecular Formula

C19H15N5O2S

Molecular Weight

377.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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