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BIRM 271

Product Specifications

CAS Number

149106-77-4

Target

LTR, Leukotriene Receptor, Phospholipase

Related Pathways

Metabolism, GPCR/G Protein, Immunology/Inflammation

Purity

0.9978

Bioactivity

BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and BIRM 270 are enantiomers that inhibit the production of leukotriene B4 with IC50 of 40 nM.

Smiles

N([C@H](CC1CCCCC1)C2=CC=CC=N2)C=3OC=4C(N3)=CC(C)=CC4

Molecular Formula

C21H25N3O

Molecular Weight

335.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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