BIRM 271
Product Specifications
CAS Number
149106-77-4
Target
LTR|||Leukotriene Receptor|||Phospholipase
Related Pathways
Metabolism|||GPCR/G Protein|||Immunology/Inflammation
Purity
0.9978
Bioactivity
BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and BIRM 270 are enantiomers that inhibit the production of leukotriene B4 with IC50 of 40 nM.
Smiles
N([C@H](CC1CCCCC1)C2=CC=CC=N2)C=3OC=4C(N3)=CC(C)=CC4
Molecular Formula
C21H25N3O
Molecular Weight
335.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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