EP3 antagonist 4
Product Specifications
CAS Number
2408297-80-1
Target
Prostaglandin Receptor
Related Pathways
Immunology/Inflammation, GPCR/G Protein
Bioactivity
EP3 antagonist 4 is an EP3 antagonist that inhibits hEP with a Ki of 2 nM. EP3 antagonist 4 showed low in vivo clearance, high oral AUC and good bioavailability in complete PK studies in rats. EP3 antagonist 4 can be used to study diabetes and cellular dysfunction.
Smiles
C(N1C\2=C(C=N1)CCC/C2=C(\CNC(NS(=O)(=O)C3=CC(C)=C(Cl)S3)=O)/F)C4=C(Cl)C=C(Cl)C=C4
Molecular Formula
C22H20Cl3FN4O3S2
Molecular Weight
577.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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