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EP3 antagonist 4

Product Specifications

CAS Number

2408297-80-1

Target

Prostaglandin Receptor

Related Pathways

Immunology/Inflammation, GPCR/G Protein

Bioactivity

EP3 antagonist 4 is an EP3 antagonist that inhibits hEP with a Ki of 2 nM. EP3 antagonist 4 showed low in vivo clearance, high oral AUC and good bioavailability in complete PK studies in rats. EP3 antagonist 4 can be used to study diabetes and cellular dysfunction.

Smiles

C(N1C\2=C(C=N1)CCC/C2=C(\CNC(NS(=O)(=O)C3=CC(C)=C(Cl)S3)=O)/F)C4=C(Cl)C=C(Cl)C=C4

Molecular Formula

C22H20Cl3FN4O3S2

Molecular Weight

577.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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