LMTK3-IN-1
Product Specifications
CAS Number
2764850-23-7
Target
C-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
Purity
>99.99%
Bioactivity
Lmtk3-in-1 is a potent ATP-competitive lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 ?M) inhibitor that degrades LMTK3 through the ubiquitin proteasome pathway. LMTK3-IN-1 has shown anticancer activity in a variety of cancer cell lines and in vivo BC mouse models. LMTK3-IN-1 (10-20 ?M) can induce the apoptosis of BC cell line.
Smiles
FC(F)(F)OC1=CC=CC(=C1)C2=CN=C3C=CC(=NN32)C=4C=CN=CC4
Molecular Formula
C18H11F3N4O
Molecular Weight
356.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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