What is the catalog number for JC2-11?

The catalog number for JC2-11 is T77579.

What sizes are available for JC2-11?

JC2-11 is available in the following size(s): 1 mg, 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 500 mg.

How many pack sizes does JC2-11 come in?

JC2-11 is available in 8 different pack sizes.

JC2-11 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures JC2-11?

JC2-11 is manufactured by Molfinity.

What is the estimated delivery time for JC2-11?

Estimated delivery time for JC2-11 is approximately 10 business day(s), depending on your location.

JC2-11

Product Specifications

CAS Number

937820-89-8

Target

NOD-like Receptor (NLR), AIM2, IL Receptor, Caspase, Dehydrogenase, ROS

Related Pathways

Immunology/Inflammation, Metabolism, Apoptosis, Proteases/Proteasome

Purity

0.9988

Bioactivity

JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen species (ROS) production and caspase-1 activity.JC2-11 reduces caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) activity in inflammatory vesicles. JC2-11 reduced caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) release from inflammatory vesicles.