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Nurr1 agonist 2

Product Specifications

CAS Number

742058-34-0

Target

NR4A|||Others

Related Pathways

Others|||Endocrinology/Hormones

Purity

0.9878

Bioactivity

Nurr1 agonist 2 is a Nurr1 agonist with an EC50 value of 0.07 ?M. Nurr1 agonist 2 increases the mRNA expression of the Nurr1-regulated genes tyrosine hydroxylase (TH) and vesicular amino acid transporter 2 (VMAT2) . Nurr1 agonist 2 binds to the recombinant Nurr1 ligand-binding domain (LBD) with a Kd of 0.14 ?M. Nurr1 agonist 2 can be used to study parkinsonism.

Smiles

C(O)(=O)C=1SC(=CC1)C2=CC=C(OCC3=CC=CC=C3)C=C2

Molecular Formula

C18H14O3S

Molecular Weight

310.37

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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