MSU-42011
Product Specifications
CAS Number
2456434-36-7
Target
NOS, Retinoid Receptor, Ras, Lipid, Kras, PERK, NO Synthase
Related Pathways
Apoptosis, Metabolism, Immunology/Inflammation, MAPK
Purity
0.996
Bioactivity
MSU-42011 is an orally active retinoid X receptor-like (RXR) agonist. It potently inhibits the expression of iNOS, low SREBP-induced and activated RXR, and p-ERK at the protein level. MSU-42011 has demonstrated antitumor activity in a [kras]-driven mouse model of lung cancer and is effective for the treatment of preclinical [kras]-driven lung cancer with immunomodulatory activity.
Smiles
N(CC(C)C)(C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1)C2=CC=C(C(O)=O)C=N2
Molecular Formula
C24H34N2O2
Molecular Weight
382.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
31815061 1.0 µg DNA
NHP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
029517-Biotin 100 µL
Interleukin-10 (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF, Il10, Il-10) (Biotin)
Sign In for Pricing
View Details