Sirtratumab

Product Specifications

CAS Number

1824663-82-2

Target

Others

Related Pathways

Others

Purity

0.9878

Bioactivity

Sirtratumab (also known as AGS15C / Ha15-10ac12) is a human monoclonal antibody targeting SLITRK6. It is used in cancer research, particularly in tumor models with high SLITRK6 expression, to investigate the role of SLITRK6 in tumor growth, proliferation, migration, and other biological processes. As a candidate antibody for ADC development, an antibody–drug conjugate derived from Sirtratumab (Sirtratumab vedotin / AGS15E) has been developed to selectively deliver cytotoxic agents to SLITRK6-positive tumor cells, thereby enhancing targeting specificity.