HDAC-IN-57
Product Specifications
CAS Number
2716217-79-5
Target
Apoptosis|||HDAC
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Apoptosis
Purity
0.9862
Bioactivity
HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 nM, and 107 nM, respectively. HDAC-IN-57 inhibits LSD1 with an IC50 value of 1.34 ??. HDAC-IN-57 has anti-tumor activity and can induce apoptosis.
Smiles
C(NCC1=CC=C(C(NO)=O)C=C1)(=O)C=2C=C(N=CC2)C3=CC=C(OC)C=C3
Molecular Formula
C21H19N3O4
Molecular Weight
377.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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