N, O-Didansyl-L-tyrosine cyclohexylammonium
Product Specifications
CAS Number
102783-47-1
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
N, O-Didansyl-L-tyrosine cyclohexylammonium is a potent and selective inhibitor of thymidylate synthase (TS), showing activity against TS in Escherichia coli, Lactobacillus casei, and humans, with IC50 values of 5.0, 3.4, and 119 μM, respectively [1].
Smiles
NC1CCCCC1.CN(C)c1cccc2c(cccc12)S(=O)(=O)N[C@@H](Cc1ccc(OS(=O)(=O)c2cccc3c(cccc23)N(C)C)cc1)C(O)=O
Molecular Formula
C39H46N4O7S2
Molecular Weight
746.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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