Petosemtamab
Product Specifications
CAS Number
2213450-26-9
Target
EGFR
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis
Purity
>95%
Bioactivity
Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM) . Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab can be used in the study of solid tumors such as head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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