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Dalotuzumab

Product Specifications

CAS Number

1005389-60-5

Target

IGF-1R, Apoptosis

Related Pathways

Apoptosis, Tyrosine Kinase/Adaptors

Purity

0.993

Bioactivity

Dalotuzumab (MK-0646) is a recombinant humanized IgG1 monoclonal antibody that specifically targets the insulin-like growth factor 1 receptor (IGF-1R) . its mechanism of action involves the inhibition of IGF-mediated oncogenic signaling, which subsequently induces apoptosis and cell cycle arrest in tumor cells, and it has demonstrated enhanced antitumor efficacy when used in combination with other chemotherapeutic agents.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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