Dalotuzumab
Product Specifications
CAS Number
1005389-60-5
Target
IGF-1R, Apoptosis
Related Pathways
Apoptosis, Tyrosine Kinase/Adaptors
Purity
0.993
Bioactivity
Dalotuzumab (MK-0646) is a recombinant humanized IgG1 monoclonal antibody that specifically targets the insulin-like growth factor 1 receptor (IGF-1R) . its mechanism of action involves the inhibition of IGF-mediated oncogenic signaling, which subsequently induces apoptosis and cell cycle arrest in tumor cells, and it has demonstrated enhanced antitumor efficacy when used in combination with other chemotherapeutic agents.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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