Ulocuplumab
Product Specifications
CAS Number
1375830-34-4
Target
CXCR, Apoptosis
Related Pathways
GPCR/G Protein, Autophagy, Apoptosis, Immunology/Inflammation
Purity
0.975
Bioactivity
Ulocuplumab (BMS-936564) is a fully human anti-CXCR4 IgG4 antibody.Ulocplumab exhibits antitumor activity in acute myeloid leukemia (AML), non-Hodgkin's lymphoma (NHL), and multiple myeloma transplantation models.Ulocplumab inhibits the migration of chronic lymphocytic leukemia (CLL) cells under CXCR4 activation, induces apoptosis, and inhibits the growth and migration of cancer cells. Ulocplumab inhibits CXCL12-mediated chronic lymphocytic leukemia (CLL) cell migration in response to CXCR4 activation and induces apoptosis.)
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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