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Seribantumab

Product Specifications

CAS Number

1334296-12-6

Target

EGFR|||HER|||Apoptosis

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis|||JAK/STAT signaling

Purity

0.9626

Bioactivity

Seribantumab (MM 121) is a humanized monoclonal antibody targeting HER3, inhibiting NRG1-induced growth in MCF-7 cells and patient-derived breast and lung cancer cells harboring NRG1 fusions or amplifications. It also induces apoptosis in MDA-MB-175-VII and LUAD-0061AS3 cells.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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