Conatumumab
Product Specifications
CAS Number
896731-82-1
Target
TNF
Related Pathways
Apoptosis
Purity
>95%
Bioactivity
Conatumumab (AMG 655) is a monoclonal agonist antibody targeting human death receptor 5 [DR5, TRAILR2] with a dissociation constant (Kd) of 1 nM for long DR5 and 0.8 nM for short DR5. It induces apoptosis in various tumor types through caspase activation and can be used to study advanced solid tumors.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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