Emapalumab
Product Specifications
CAS Number
1709815-23-5
Target
COX|||IFNAR
Related Pathways
Neuroscience|||Immunology/Inflammation
Purity
0.9756
Bioactivity
Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-? and to IFN-? bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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