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Emapalumab

Product Specifications

CAS Number

1709815-23-5

Target

COX|||IFNAR

Related Pathways

Neuroscience|||Immunology/Inflammation

Purity

0.9756

Bioactivity

Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-? and to IFN-? bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH) .

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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