What is the catalog number for Fremanezumab?

The catalog number for Fremanezumab is T76680.

What sizes are available for Fremanezumab?

Fremanezumab is available in the following size(s): 1 mg, 5 mg, 10 mg.

How many pack sizes does Fremanezumab come in?

Fremanezumab is available in 3 different pack sizes.

Is Fremanezumab in stock?

Fremanezumab is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Fremanezumab?

Fremanezumab is manufactured by Molfinity.

What is the estimated delivery time for Fremanezumab?

Estimated delivery time for Fremanezumab is approximately 10 business day(s), depending on your location.

Fremanezumab

Product Specifications

CAS Number

1655501-53-3

Target

CGRP Receptor

Related Pathways

GPCR/G Protein, Neuroscience

Purity

0.976

Bioactivity

Fremanezumab (TEV-48125) is a humanised monoclonal antibody targeting CGRP, capable of neutralising human (IC50=7.94 nM), mouse (IC50=19.6 nM) and rat CGRP, and is indicated for the prevention of migraine. Fremanezumab inhibits CGRP's vasodilatory effects in the basilar artery constriction segment and suppresses activation of A-δ and high-threshold (HT) neurons in the meningeal nociceptive system triggered by cortical spreading depression (CSD) in rats. In vitro, Fremanezumab counteracts CGRP's immunosuppressive effects on microglia and lymphocytes.