HMCH-1R antagonist 1

HMCH-1R Antagonist 1 (Compound 30) serves as an effective and selective antagonist for the human melanin-concentrating hormone receptor 1 (hMCHR1), exhibiting a K_B value of 3.6 nM. It possesses the ability to bind to hMCHR1 and hMCHR2, with IC_50 values of 65 nM and 49 nM, respectively. This compound is applicable in metabolic research [1].

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