Sulanemadlin
Product Specifications
CAS Number
1451199-98-6
Target
MDM-2/p53
Related Pathways
Apoptosis
Bioactivity
Sulanemadlin (ALRN-6924) is a potent peptidomimetic macrocycle that inhibits p53-MDM2 and p53-MDMX protein-protein interactions, serving as a valuable tool for cancer research [1].
Smiles
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@]1(C)CCCCCC\C=C\CCC[C@](C)(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(O)=O)NC1=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(N)=O
Molecular Formula
C95H140N20O23
Molecular Weight
1930.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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