GR 83074
Product Specifications
CAS Number
141636-44-4
Target
Neurokinin receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
GR 83074 is a potent and selective antagonist of the NK-2 (Neurokinin Receptor) with a 340-fold selectivity over NK-1 and a pK_B value of 8.23. It does not act as an antagonist for NK-3, affirming its specificity [1].
Smiles
CCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)OC(C)(C)C)C(N)=O
Molecular Formula
C50H72N12O9
Molecular Weight
985.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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