Targefrin
Product Specifications
Target
Ephrin Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Targefrin is a potent antagonist targeting EphA2, exhibiting a dissociation constant of 21 nM and an IC50 value of 10.8 nM for the EphA2-LBD. It promotes receptor internalization and degradation across multiple pancreatic cancer cell lines [1].
Molecular Formula
C85H116F3N19O15
Molecular Weight
1700.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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