A-Helical Corticotropin Releasing Factor (12-41)
Product Specifications
CAS Number
158535-55-8
Target
CRFR
Related Pathways
GPCR/G Protein
Bioactivity
?-Helical Corticotropin Releasing Factor (12-41), a 30-amino-acid ?-helical analogue of corticotropin releasing factor/hormone (CRF), is a hypothalamic hormone that promotes adrenocorticotrophic hormone (ACTH) secretion. This compound counteracts CRF's stimulatory effect on ACTH secretion [1] [2].
Smiles
[C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)C)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CC(C)C)=O)C)=O)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)C)=O)CCC(O)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)C)=O)CCCCN)=O)C)=O)CCSC)=O)CCC(O)=O)=O)CC(C)C)=O)CCSC)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O)NC([C@H](CC2=CC=CC=C2)N)=O
Molecular Formula
C152H251N43O47S2
Molecular Weight
3497.01
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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