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PE 22-28

Product Specifications

CAS Number

1801959-12-5

Target

Potassium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

PE 22-28, a TREK-1 inhibitor exhibiting an IC50 value of 0.12 nM, is a 7 amino-acid peptide. It serves as a foundational sequence for the creation of analogs through chemical modifications and amino-acid substitution. This compound is utilized in depression research [1].

Smiles

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CN)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

Molecular Formula

C35H55N11O9

Molecular Weight

773.88

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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