PE 22-28
Product Specifications
CAS Number
1801959-12-5
Target
Potassium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
PE 22-28, a TREK-1 inhibitor exhibiting an IC50 value of 0.12 nM, is a 7 amino-acid peptide. It serves as a foundational sequence for the creation of analogs through chemical modifications and amino-acid substitution. This compound is utilized in depression research [1].
Smiles
CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CN)C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Molecular Formula
C35H55N11O9
Molecular Weight
773.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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