Pep19-2.5

Product Specifications

CAS Number

1322711-38-5

Target

Pyroptosis

Related Pathways

Immunology/Inflammation|||Apoptosis

Bioactivity

Pep19-2.5, a synthetic antitoxin peptide, inhibits the intracellular signaling cascade triggered by endotoxins by blocking the activity of lipopeptides (LP) and lipopolysaccharides (LPS) mediated through both transmembrane and cytosolic pattern recognition receptors (PRRs) . This action disrupts the signaling pathways that normally result in inflammation and cell pyroptosis [1].

Smiles

C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(NCC(O)=O)=O)=O)=O)NC([C@H](CC4=CC=CC=C4)NC([C@@H](NC(CNC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@H](CC=6C=7C(NC6)=CC=CC7)NC([C@@H](NC([C@H](CC8=CC=CC=C8)NC([C@@H](NC([C@@H](NC([C@H](CC9=CC=C(O)C=C9)NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CS)=O)CCCCN)=O)CCCCN)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)=O)CCCCN)=O)=O)CCCCN)=O)=O)C=%10C=%11C(NC%10)=CC=CC%11