Ac-FEID-CMK TFA
Product Specifications
Target
Pyroptosis
Related Pathways
Apoptosis, Immunology/Inflammation
Purity
0.95
Bioactivity
Ac-FEID-CMK TFA is a selective zebrafish GSDMEb-derived peptide inhibitor that reduces mortality and renal injury in infectious shock. It inhibits pyroptosis in vivo, attenuates septic AKI (acute kidney injury), and inhibits the caspy2-mediated atypical inflammatory vesicle pathway.
Smiles
CC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](CC)C)C(N[C@H](CC(O)=O)C(CCl)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C29H38ClF3N4O11
Molecular Weight
711.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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