CKLF1-C27

Product Specifications

CAS Number

891861-48-6

Target

ERK, CCR

Related Pathways

Microbiology/Virology, Immunology/Inflammation, GPCR/G Protein, MAPK

Bioactivity

CKLF1-C27, a C-terminal peptide of CKLF1, effectively binds to and activates the CCR4 receptor, triggering the ERK1/2 pathway. Competing with CKLF1 for the CCR4 receptor, it neutralizes CKLF1's cellular effects. Additionally, CKLF1-C27 significantly promotes the proliferation of HUVECs and holds promise for psoriasis research [1].

Smiles

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