PINT-87aa

PINT-87aa, an 87-amino acid (aa) peptide encoded by the circular form of the long intergenic non-protein-coding RNA p53-induced transcript (LINC-PINT), directly interacts with the polymerase associated factor complex (PAF1c) to inhibit the transcriptional elongation of multiple oncogenes, effectively suppressing glioblastoma cell proliferation both in vitro and in vivo [1].