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Human PD-L1 inhibitor V

Product Specifications

CAS Number

2815311-61-4

Target

PD-1/PD-L1

Related Pathways

Immunology/Inflammation, Apoptosis, Cell Cycle/Checkpoint

Bioactivity

Human PD-L1 Inhibitor V is a peptide that binds to the human PD-1 protein with an affinity characterized by a dissociation constant (Kd) of 3.32 μM, effectively inhibiting the hPD-1/hPD-L1 interaction [1].

Smiles

[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@H](CC(C)C)N)=O)CC(O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)CCSC)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)[C@H](C)C)=O

Molecular Formula

C65H104N20O18S

Molecular Weight

1485.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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