Cyclo (RGDfC) TFA
Product Specifications
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Purity
0.9859
Bioactivity
Cyclo (RGDfC) TFA (Cyclo (Arg-Gly-Asp-D-Phe-Cys) TFA) is a cyclic pentapeptide, a cyclic RGD polypeptide with high affinity for αvβ3, which is capable of disrupting cellular integrin interactions. Cyclo (RGDfC) TFA inhibits pluripotent gene expression in embryonic stem cells (ESCs) and inhibits tumorigenic potential of mESCs in vivo. Cyclo (RGDfC) TFA inhibits the tumorigenic potential of mESC. Cyclo (RGDfC) TFA can be used for tumor-related studies.
Smiles
O=C([C@@H](NC(CNC([C@@H](NC([C@@H](NC1=O)CS)=O)CCCNC(N)=N)=O)=O)CC(O)=O)N[C@@H]1CC2=CC=CC=C2.OC(C(F)(F)F)=O
Molecular Formula
C26H35F3N8O9S
Molecular Weight
692.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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