Buforin II

Buforin II, a powerful antimicrobial peptide originating from Buforin I (a protein extracted from the Asian toad Bufo bufo gargarizans's stomach), exhibits broad-spectrum antimicrobial properties against both Gram-positive and Gram-negative bacteria [1].

C([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC([C@H]([C@@H](C)O)N)=O)=O)CO)=O)CO)=O)CCCNC(=N)N)=O)C)=O)=O)CC(C)C)=O)CCC(N)=O)=O)(=O)N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)[C@H](C)C)=O)CCCNC(=N)N)=O)=O)[C@H](C)C)=O)CCC2