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Malantide TFA

Product Specifications

Target

PKA, PKC

Related Pathways

Chromatin/Epigenetic, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors

Bioactivity

Malantide TFA, a synthetic dodecapeptide, originates from the phosphorylation site targeted by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Exhibiting a high specificity for PKA with a Michaelis constant (Km) of 15 μM, this compound demonstrates more than 90% inhibition of substrate phosphorylation in the presence of protein inhibitor (PKI) across various rat tissue extracts [1]. Moreover, Malantide TFA acts as an effective substrate for Protein Kinase C (PKC) with a Km of 16 μM [2].

Molecular Formula

C74H125F3N22O23

Molecular Weight

1747.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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