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TAT-cyclo-CLLFVY TFA

Product Specifications

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Metabolism|||Chromatin/Epigenetic

Bioactivity

TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor targeting HIF-1 heterodimerization to mitigate hypoxia signaling within cancer cells. It effectively disrupts the protein-protein interaction between HIF-1? and HIF-1?, with an inhibitory concentration (IC 50) of 1.3 ?M [1].

Molecular Formula

C113H189F3N42O26S2

Molecular Weight

2673.1

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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