TAT-cyclo-CLLFVY TFA

TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor targeting HIF-1 heterodimerization to mitigate hypoxia signaling within cancer cells. It effectively disrupts the protein-protein interaction between HIF-1? and HIF-1?, with an inhibitory concentration (IC 50) of 1.3 ?M [1].