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Thalifendine chloride

Product Specifications

CAS Number

4668-19-3

Target

Parasite, Drug Metabolite

Related Pathways

Metabolism, Microbiology/Virology

Bioactivity

Thalifendine chloride is a metabolite of berberine, wherein the methoxy group at the C-10 position undergoes demethylation by CYP51. It exhibits cytotoxicity against P-388 mouse leukaemia cells (ED50 = 0.84 μM) and demonstrates weak inhibitory activity against Plasmodium falciparum.

Smiles

O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1O.[Cl-]

Molecular Formula

C19H16ClNO4

Molecular Weight

357.79

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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