Thalifendine chloride
Product Specifications
CAS Number
4668-19-3
Target
Parasite|||Drug Metabolite
Related Pathways
Metabolism|||Microbiology/Virology
Bioactivity
Thalifendine chloride is a metabolite of berberine, wherein the methoxy group at the C-10 position undergoes demethylation by CYP51. It exhibits cytotoxicity against P-388 mouse leukaemia cells (ED?? = 0.84 ?M) and demonstrates weak inhibitory activity against Plasmodium falciparum.
Smiles
O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1O.[Cl-]
Molecular Formula
C19H16ClNO4
Molecular Weight
357.79
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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