PM050489
Product Specifications
CAS Number
960210-97-3
Target
Others, Microtubule Associated
Related Pathways
Others, Cytoskeletal Signaling
Bioactivity
PM050489, a potent polyketone inhibitor of Microtubule/Tubulin isolated from the Madagascan sponge Lithoplocamia lithistoides, effectively inhibits mitosis with an IC 50 value of 26.4 nM. This compound exhibits antitumor activity, making it relevant for cancer research [1] [2].
Smiles
[C@@H](/C=C(/C=C\C=C/C(N[C@H](C(N/C=C\C[C@H](C/C=C(\C)/Cl)OC(N)=O)=O)[C@@](C)(C)C)=O)\C)(C)[C@]1(OC(=O)C(OC)=CC1)[H]
Molecular Formula
C31H44ClN3O7
Molecular Weight
606.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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