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PM050489

Product Specifications

CAS Number

960210-97-3

Target

Others, Microtubule Associated

Related Pathways

Others, Cytoskeletal Signaling

Bioactivity

PM050489, a potent polyketone inhibitor of Microtubule/Tubulin isolated from the Madagascan sponge Lithoplocamia lithistoides, effectively inhibits mitosis with an IC 50 value of 26.4 nM. This compound exhibits antitumor activity, making it relevant for cancer research [1] [2].

Smiles

[C@@H](/C=C(/C=C\C=C/C(N[C@H](C(N/C=C\C[C@H](C/C=C(\C)/Cl)OC(N)=O)=O)[C@@](C)(C)C)=O)\C)(C)[C@]1(OC(=O)C(OC)=CC1)[H]

Molecular Formula

C31H44ClN3O7

Molecular Weight

606.15

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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