7-Hydroxyneolamellarin A
Product Specifications
CAS Number
959662-26-1
Target
VEGFR, HIF/HIF Prolyl-Hydroxylase, Others
Related Pathways
Metabolism, Others, Tyrosine Kinase/Adaptors, Angiogenesis, Chromatin/Epigenetic
Bioactivity
7-Hydroxyneolamellarin A, a natural product from the sponge Dendrilla nigra, serves as a potent inhibitor of hypoxia-inducible factor-1α (HIF-1α) . It effectively reduces the accumulation of HIF-1α protein and suppresses vascular epidermal growth factor (VEGF) transcriptional activity, making it valuable in cancer research [1].
Smiles
C(C(O)C1=CC=C(O)C=C1)(=O)N2C=C(C(=C2)C3=CC=C(O)C=C3)C4=CC=C(O)C=C4
Molecular Formula
C24H19NO5
Molecular Weight
401.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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