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7-Hydroxyneolamellarin A

Product Specifications

CAS Number

959662-26-1

Target

VEGFR, HIF/HIF Prolyl-Hydroxylase, Others

Related Pathways

Metabolism, Others, Tyrosine Kinase/Adaptors, Angiogenesis, Chromatin/Epigenetic

Bioactivity

7-Hydroxyneolamellarin A, a natural product from the sponge Dendrilla nigra, serves as a potent inhibitor of hypoxia-inducible factor-1α (HIF-1α) . It effectively reduces the accumulation of HIF-1α protein and suppresses vascular epidermal growth factor (VEGF) transcriptional activity, making it valuable in cancer research [1].

Smiles

C(C(O)C1=CC=C(O)C=C1)(=O)N2C=C(C(=C2)C3=CC=C(O)C=C3)C4=CC=C(O)C=C4

Molecular Formula

C24H19NO5

Molecular Weight

401.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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