DCDAPH
Product Specifications
CAS Number
125113-96-4
Target
Beta Amyloid|||Others
Related Pathways
Neuroscience|||Others
Bioactivity
DCDAPH (Compound 2c), a novel smart near-infrared fluorescence (NIRF) probe, efficiently detects ?-amyloid (A?) plaques with an excitation/emission wavelength (? ex /? em) of 597/665 nm in PBS. It demonstrates high affinity for A? aggregates, exhibiting a dissociation constant (Kd) of 27 nM and an inhibition constant (Ki) of 37 nM. Furthermore, DCDAPH exhibits favorable blood-brain barrier permeability, qualifying it as a suitable agent for both in vitro and in vivo detection of A? plaques [1].
Smiles
C(=CC=CC=C(C#N)C#N)C1=CC=C(N(C)C)C=C1
Molecular Formula
C16H15N3
Molecular Weight
249.31
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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