Taurodeoxycholic acid
Product Specifications
CAS Number
516-50-7
Target
PKA, Endogenous Metabolite, Apoptosis, NF-κB, PARP, Caspase, Calcium Channel, GPCR19
Related Pathways
DNA Damage/DNA Repair, Tyrosine Kinase/Adaptors, Apoptosis, Metabolism, Proteases/Proteasome, GPCR/G Protein, NF-κB, Membrane transporter/Ion channel, Chromatin/Epigenetic
Purity
0.9922
Bioactivity
Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic acid inhibits apoptosis by blocking calcium-mediated apoptotic pathways and by activation of caspase-12. Taurodeoxycholic acid has neuroprotective activity and has been used to study 3-nitropropionic acid-induced or stabilized hereditary Huntington's chorea (HD) .
Smiles
C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C[C@@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(NCCS(=O)(=O)O)=O)C)[H])[H]
Molecular Formula
C26H45NO6S
Molecular Weight
499.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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